Design properties of hydrogel tissue-engineering scaffolds
نویسندگان
چکیده
منابع مشابه
Hydrogel scaffolds for tissue engineering: Progress and challenges
Designing of biologically active scaffolds with optimal characteristics is one of the key factors for successful tissue engineering. Recently, hydrogels have received a considerable interest as leading candidates for engineered tissue scaffolds due to their unique compositional and structural similarities to the natural extracellular matrix, in addition to their desirable framework for cellular...
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Hydrogels closely resemble the extracellular matrix (ECM) and can support cell proliferation while new tissue is formed, making them materials of choice as tissue engineering scaffolds. However, their sometimes-poor mechanical properties can hinder their application. The addition of meshes of nanofibers embedded in their matrix forms a composite that draws from the advantages of both components...
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Heart valve-related disorders are among the major causes of death worldwide. Although prosthetic valves are widely used to treat this pathology, current prosthetic grafts cannot grow with the patient while maintaining normal valve mechanical and hemodynamic properties. Tissue engineering may provide a possible solution to this issue through using biodegradable scaffolds and patients' own cells....
متن کاملCardiac Extracellular Matrix-Fibrin Hydrogel Scaffolds with Tunable Properties for Cardiac Tissue Engineering
Introduction: Heart disease is currently the leading cause of death worldwide [1]. The majority of available therapies are geared toward slowing down the progression of heart disease and not toward restoring the contractile function of the affected tissues [2]. Extracellular matrix (ECM) obtained from decellularized cardiac tissue is a promising scaffold material that can be utilized to repair ...
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Electrospinning has been recognized as an efficient technique for the fabrication of polymernanofibers. Recently, various polymers have successfully been electrospun into ultrafine fibers.Electrospinning is an extremely promising method for the preparation of tissue engineering scaffolds.In this study, nanofibers gelatin was electrospun at 20% v/v optimized content. To produce...
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ژورنال
عنوان ژورنال: Expert Review of Medical Devices
سال: 2011
ISSN: 1743-4440,1745-2422
DOI: 10.1586/erd.11.27